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Enhanced transduction of CAR-negative cells by protein IX-gene deleted adenovirus 5 vectors

In human adenoviruses (HAdV), 240 copies of the 14.3-kDa minor capsid protein IX stabilize the capsid. Three N-terminal domains of protein IX form triskelions between hexon capsomers. The C-terminal domains of four protein IX monomers associate near the facet periphery. The precise biological role o...

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Detalles Bibliográficos
Autores principales: de Vrij, Jeroen, van den Hengel, Sanne K., Uil, Taco G., Koppers-Lalic, Danijela, Dautzenberg, Iris J.C., Stassen, Oscar M.J.A., Bárcena, Montserrat, Yamamoto, Masato, de Ridder, Corrina M.A., Kraaij, Robert, Kwappenberg, Kitty M., Schilham, Marco W., Hoeben, Rob C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. Published by Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111976/
https://www.ncbi.nlm.nih.gov/pubmed/21130482
http://dx.doi.org/10.1016/j.virol.2010.10.040