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Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate
Porcine reproductive and respiratory syndrome virus (PRRSV) is known to interfere with the signaling of type I interferons (IFNs). Here we found PRRSV A2MC2 induced type I IFNs in cultured cells. A2MC2 replication in MARC-145 cells resulted in the synthesis of IFN-α2 protein, transcript elevation of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc. Published by Elsevier Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111977/ https://www.ncbi.nlm.nih.gov/pubmed/22704065 http://dx.doi.org/10.1016/j.virol.2012.05.015 |