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Induction of type I interferons by a novel porcine reproductive and respiratory syndrome virus isolate

Porcine reproductive and respiratory syndrome virus (PRRSV) is known to interfere with the signaling of type I interferons (IFNs). Here we found PRRSV A2MC2 induced type I IFNs in cultured cells. A2MC2 replication in MARC-145 cells resulted in the synthesis of IFN-α2 protein, transcript elevation of...

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Detalles Bibliográficos
Autores principales:	Nan, Yuchen, Wang, Rong, Shen, Meiyan, Faaberg, Kay S., Samal, Siba K., Zhang, Yan-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. Published by Elsevier Inc. 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111977/ https://www.ncbi.nlm.nih.gov/pubmed/22704065 http://dx.doi.org/10.1016/j.virol.2012.05.015

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