Synthesis of 3-fluoro-6-S-(2-S-pyridyl) nucleosides as potential lead cytostatic agents

The 3-deoxy-3-fluoro-6-S-(2-S-pyridyl)-6-thio-β-d-glucopyranosyl nucleoside analogs 7 were prepared via two facile synthetic routes. Their precursors, 3-fluoro-6-thio-glucopyranosyl nucleosides 5a-e, were obtained by the sequence of deacetylation of 3-deoxy-3-fluoro-β-d-glucopyranosyl nucleosides 2a...

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Detalles Bibliográficos
Autores principales: Tsoukala, Evangelia, Tzioumaki, Niki, Manta, Stella, Riga, Alexandra, Balzarini, Jan, Komiotis, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112006/
https://www.ncbi.nlm.nih.gov/pubmed/20817215
http://dx.doi.org/10.1016/j.bioorg.2010.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112006/
https://www.ncbi.nlm.nih.gov/pubmed/20817215
http://dx.doi.org/10.1016/j.bioorg.2010.08.001

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