S gene and 5a accessory gene are responsible for the attenuation of virulent infectious bronchitis coronavirus

To explore the critical genes associated with infectious bronchitis virus (IBV) virulence, we compared the genome sequences of virulent YN strain and its attenuated strain aYN. Accumulation of mutations in the S gene and the accessory gene 5a were observed, suggesting a potential role in the loss of...

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Detalles Bibliográficos
Autores principales: Zhao, Ye, Cheng, Jinlong, Yan, Shihong, Jia, Wenfeng, Zhang, Keran, Zhang, Guozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112010/
https://www.ncbi.nlm.nih.gov/pubmed/31078931
http://dx.doi.org/10.1016/j.virol.2019.04.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112010/
https://www.ncbi.nlm.nih.gov/pubmed/31078931
http://dx.doi.org/10.1016/j.virol.2019.04.014

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