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S gene and 5a accessory gene are responsible for the attenuation of virulent infectious bronchitis coronavirus
To explore the critical genes associated with infectious bronchitis virus (IBV) virulence, we compared the genome sequences of virulent YN strain and its attenuated strain aYN. Accumulation of mutations in the S gene and the accessory gene 5a were observed, suggesting a potential role in the loss of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Authors. Published by Elsevier Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112010/ https://www.ncbi.nlm.nih.gov/pubmed/31078931 http://dx.doi.org/10.1016/j.virol.2019.04.014 |