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Cyclophilins and cyclophilin inhibitors in nidovirus replication
Cyclophilins (Cyps) belong to the family of peptidyl-prolyl isomerases (PPIases). The PPIase activity of most Cyps is inhibited by the immunosuppressive drug cyclosporin A and several of its non-immunosuppressive analogs, which can also block the replication of nidoviruses (arteriviruses and coronav...
Autores principales: | de Wilde, Adriaan H., Pham, Uyen, Posthuma, Clara C., Snijder, Eric J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112023/ https://www.ncbi.nlm.nih.gov/pubmed/30014857 http://dx.doi.org/10.1016/j.virol.2018.06.011 |
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