Wild-type human coronaviruses prefer cell-surface TMPRSS2 to endosomal cathepsins for cell entry

Human coronaviruses (HCoVs) enter cells via two distinct pathways: the endosomal pathway using cathepsins to activate spike protein and the cell-surface or early endosome pathway using extracellular proteases such as transmembrane protease serine 2 (TMPRSS2). We previously reported that clinical iso...

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Detalles Bibliográficos
Autores principales: Shirato, Kazuya, Kawase, Miyuki, Matsuyama, Shutoku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112029/
https://www.ncbi.nlm.nih.gov/pubmed/29217279
http://dx.doi.org/10.1016/j.virol.2017.11.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112029/
https://www.ncbi.nlm.nih.gov/pubmed/29217279
http://dx.doi.org/10.1016/j.virol.2017.11.012

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