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Host cell autophagy promotes BK virus infection

Autophagy is important for a variety for virus life cycles. We sought to determine the role of autophagy in human BK polyomavirus (BKPyV) infection. The addition excess amino acids during viral infection reduced BKPyV infection. Perturbing autophagy levels using inhibitors, 3-MA, bafilomycin A1, and...

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Detalles Bibliográficos
Autores principales: Bouley, Stephanie J., Maginnis, Melissa S., Derdowski, Aaron, Gee, Gretchen V., O׳Hara, Bethany A., Nelson, Christian D., Bara, Anne M., Atwood, Walter J., Dugan, Aisling S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112032/
https://www.ncbi.nlm.nih.gov/pubmed/24889228
http://dx.doi.org/10.1016/j.virol.2014.03.009