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Attenuation of a virulent swine acute diarrhea syndrome coronavirus strain via cell culture passage

Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a newly identified enteric alphacoronavirus that causes fatal diarrhea in newborn piglets in China. Here, we propagated a virulent strain SADS-CoV/CN/GDWT/2017 in Vero cells for up to 83 passages. Four strains of SADS-CoV/GDWT-P7, -P18, -P48 an...

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Detalles Bibliográficos
Autores principales: Sun, Y., Cheng, J., Luo, Y., Yan, X.L., Wu, Z.X., He, L.L., Tan, Y.R., Zhou, Z.H., Li, Q.N., Zhou, L., Wu, R.T., Lan, T., Ma, J.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112038/
https://www.ncbi.nlm.nih.gov/pubmed/31580972
http://dx.doi.org/10.1016/j.virol.2019.09.009