Palmitoylation of the Alphacoronavirus TGEV spike protein S is essential for incorporation into virus-like particles but dispensable for S–M interaction

The spike protein S of coronaviruses contains a highly conserved cytoplasmic cysteine-rich motif adjacent to the transmembrane region. This motif is palmitoylated in the Betacoronaviruses MHV and SARS-CoV. Here, we demonstrate by metabolic labeling with [(3)H]-palmitic acid that the S protein of tra...

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Detalles Bibliográficos
Autores principales: Gelhaus, Sandra, Thaa, Bastian, Eschke, Kathrin, Veit, Michael, Schwegmann-Weßels, Christel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112097/
https://www.ncbi.nlm.nih.gov/pubmed/25113909
http://dx.doi.org/10.1016/j.virol.2014.07.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112097/
https://www.ncbi.nlm.nih.gov/pubmed/25113909
http://dx.doi.org/10.1016/j.virol.2014.07.035

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