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Generating and evaluating type I interferon receptor-deficient and feline TMPRSS2-expressing cells for propagating serotype I feline infectious peritonitis virus

Feline coronavirus infection can progress to a fatal infectious peritonitis, which is a widespread feline disease without an effective vaccine. Generating feline cells with reduced ability to respond to interferon (IFN) is an essential step facilitating isolation of new candidate vaccine strains. He...

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Detalles Bibliográficos
Autores principales: Mettelman, Robert C., O'Brien, Amornrat, Whittaker, Gary R., Baker, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112123/
https://www.ncbi.nlm.nih.gov/pubmed/31539770
http://dx.doi.org/10.1016/j.virol.2019.08.030