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Identification of residues on human receptor DPP4 critical for MERS-CoV binding and entry

Middle East respiratory syndrome coronavirus (MERS-CoV) infects host cells through binding the receptor binding domain (RBD) on its spike glycoprotein to human receptor dipeptidyl peptidase 4 (hDPP4). Here, we report identification of critical residues on hDPP4 for RBD binding and virus entry throug...

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Detalles Bibliográficos
Autores principales: Song, Wenfei, Wang, Ying, Wang, Nianshuang, Wang, Dongli, Guo, Jianying, Fu, Lili, Shi, Xuanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112127/
https://www.ncbi.nlm.nih.gov/pubmed/25461530
http://dx.doi.org/10.1016/j.virol.2014.10.006