Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3

Severe acute respiratory syndrome coronavirus (SARS-CoV) is an inefficient inducer of interferon (IFN) response. It expresses various proteins that effectively circumvent IFN production at different levels via distinct mechanisms. Through the construction of recombinant IBV expressing proteins 8a, 8...

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Detalles Bibliográficos
Autores principales: Wong, Hui Hui, Fung, To Sing, Fang, Shouguo, Huang, Mei, Le, My Tra, Liu, Ding Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112132/
https://www.ncbi.nlm.nih.gov/pubmed/29294448
http://dx.doi.org/10.1016/j.virol.2017.12.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112132/
https://www.ncbi.nlm.nih.gov/pubmed/29294448
http://dx.doi.org/10.1016/j.virol.2017.12.028

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