Hexacosenoyl-CoA is the most abundant very long-chain acyl-CoA in ATP binding cassette transporter D1-deficient cells

X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder caused by deleterious mutations in the ABCD1 gene. The ABCD1 protein transports very long-chain FAs (VLCFAs) from the cytosol into the peroxisome where the VLCFAs are degraded through β-oxidation. ABCD1 dysfunction leads to VLCFA accumul...

Descripción completa

Detalles Bibliográficos
Autores principales: Hama, Kotaro, Fujiwara, Yuko, Takashima, Shigeo, Hayashi, Yasuhiro, Yamashita, Atsushi, Shimozawa, Nobuyuki, Yokoyama, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112142/
https://www.ncbi.nlm.nih.gov/pubmed/32075856
http://dx.doi.org/10.1194/jlr.P119000325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112142/
https://www.ncbi.nlm.nih.gov/pubmed/32075856
http://dx.doi.org/10.1194/jlr.P119000325

Ejemplares similares