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LEFTY2/endometrial bleeding-associated factor up-regulates Na(+) Coupled Glucose Transporter SGLT1 expression and Glycogen Accumulation in Endometrial Cancer Cells

LEFTY2 (endometrial bleeding associated factor; EBAF or LEFTYA), a cytokine released shortly before menstrual bleeding, is a negative regulator of cell proliferation and tumour growth. LEFTY2 down-regulates Na(+)/H(+) exchanger activity with subsequent inhibition of glycolytic flux and lactate produ...

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Detalles Bibliográficos
Autores principales: Zeng, Ni, Okumura, Toshiyuki, Alauddin, Md, Khozooei, Shayan, Rajaxavier, Janet, Zhang, Shaqiu, Singh, Yogesh, Shi, Bing, Brucker, Sara Y., Wallwiener, Diethelm, Takeda, Satoru, Lang, Florian, Salker, Madhuri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112196/
https://www.ncbi.nlm.nih.gov/pubmed/32236143
http://dx.doi.org/10.1371/journal.pone.0230044