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Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation

Melanopsin is a visual pigment expressed in a small subset of ganglion cells in the mammalian retina known as intrinsically photosensitive retinal ganglion cells (ipRGCs) and is implicated in regulating non-image forming functions such as circadian photoentrainment and pupil constriction and contras...

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Detalles Bibliográficos
Autores principales: Valdez-Lopez, Juan C., Gulati, Sahil, Ortiz, Elelbin A., Palczewski, Krzysztof, Robinson, Phyllis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112210/
https://www.ncbi.nlm.nih.gov/pubmed/32236094
http://dx.doi.org/10.1371/journal.pone.0228121