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Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands

Cytokine signaling is transmitted by cell surface receptors which act as natural biological switches to control cellular functions such as immune reactions. Recently, we have designed synthetic cytokine receptors (SyCyRs) consisting of green fluorescent protein (GFP)- and mCherry-nanobodies fused to...

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Detalles Bibliográficos
Autores principales: Mossner, Sofie, Phan, Hoang T., Triller, Saskia, Moll, Jens M., Conrad, Udo, Scheller, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112226/
https://www.ncbi.nlm.nih.gov/pubmed/32236103
http://dx.doi.org/10.1371/journal.pone.0230804