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Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands
Cytokine signaling is transmitted by cell surface receptors which act as natural biological switches to control cellular functions such as immune reactions. Recently, we have designed synthetic cytokine receptors (SyCyRs) consisting of green fluorescent protein (GFP)- and mCherry-nanobodies fused to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112226/ https://www.ncbi.nlm.nih.gov/pubmed/32236103 http://dx.doi.org/10.1371/journal.pone.0230804 |