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Latency reversal agents modulate HIV antigen processing and presentation to CD8 T cells

Latency reversal agents (LRA) variably induce HIV re-expression in CD4 T cells but reservoirs are not cleared. Whether HIV epitope presentation is similar between latency reversal and initial infection of CD4 T cells is unknown yet crucial to define immune responses able to detect HIV-infected CD4 T...

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Detalles Bibliográficos
Autores principales: Boucau, Julie, Das, Jishnu, Joshi, Neelambari, Le Gall, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112239/
https://www.ncbi.nlm.nih.gov/pubmed/32196533
http://dx.doi.org/10.1371/journal.ppat.1008442