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Girdin is a component of the lateral polarity protein network restricting cell dissemination

Epithelial cell polarity defects support cancer progression. It is thus crucial to decipher the functional interactions within the polarity protein network. Here we show that Drosophila Girdin and its human ortholog (GIRDIN) sustain the function of crucial lateral polarity proteins by inhibiting the...

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Detalles Bibliográficos
Autores principales: Biehler, Cornélia, Wang, Li-Ting, Sévigny, Myriam, Jetté, Alexandra, Gamblin, Clémence L., Catterall, Rachel, Houssin, Elise, McCaffrey, Luke, Laprise, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112241/
https://www.ncbi.nlm.nih.gov/pubmed/32196494
http://dx.doi.org/10.1371/journal.pgen.1008674