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Girdin is a component of the lateral polarity protein network restricting cell dissemination
Epithelial cell polarity defects support cancer progression. It is thus crucial to decipher the functional interactions within the polarity protein network. Here we show that Drosophila Girdin and its human ortholog (GIRDIN) sustain the function of crucial lateral polarity proteins by inhibiting the...
Autores principales: | Biehler, Cornélia, Wang, Li-Ting, Sévigny, Myriam, Jetté, Alexandra, Gamblin, Clémence L., Catterall, Rachel, Houssin, Elise, McCaffrey, Luke, Laprise, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112241/ https://www.ncbi.nlm.nih.gov/pubmed/32196494 http://dx.doi.org/10.1371/journal.pgen.1008674 |
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