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Common Features of Enveloped Viruses and Implications for Immunogen Design for Next-Generation Vaccines

Enveloped viruses enter cells by inducing fusion of viral and cellular membranes, a process catalyzed by a specialized membrane-fusion protein expressed on their surface. This review focuses on recent structural studies of viral fusion proteins with an emphasis on their metastable prefusion form and...

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Detalles Bibliográficos
Autores principales: Rey, Felix A., Lok, Shee-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112304/
https://www.ncbi.nlm.nih.gov/pubmed/29522750
http://dx.doi.org/10.1016/j.cell.2018.02.054