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Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS

BACKGROUND: The outbreak of severe acute respiratory syndrome (SARS) in 2002 was caused by a previously unknown coronavirus—SARS coronavirus (SARS-CoV). We have developed an experimental SARS vaccine for direct immunisation of the respiratory tract, the major site of SARS-coronavirus transmission an...

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Detalles Bibliográficos
Autores principales: Bukreyev, Alexander, Lamirande, Elaine W, Buchholz, Ursula J, Vogel, Leatrice N, Elkins, William R, Claire, Marisa St, Murphy, Brian R, Subbarao, Kanta, Collins, Peter L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112367/
https://www.ncbi.nlm.nih.gov/pubmed/15220033
http://dx.doi.org/10.1016/S0140-6736(04)16501-X