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Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS
BACKGROUND: The outbreak of severe acute respiratory syndrome (SARS) in 2002 was caused by a previously unknown coronavirus—SARS coronavirus (SARS-CoV). We have developed an experimental SARS vaccine for direct immunisation of the respiratory tract, the major site of SARS-coronavirus transmission an...
Autores principales: | Bukreyev, Alexander, Lamirande, Elaine W, Buchholz, Ursula J, Vogel, Leatrice N, Elkins, William R, Claire, Marisa St, Murphy, Brian R, Subbarao, Kanta, Collins, Peter L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112367/ https://www.ncbi.nlm.nih.gov/pubmed/15220033 http://dx.doi.org/10.1016/S0140-6736(04)16501-X |
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