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Vaccination of mice with recombinant baculovirus expressing spike or nucleocapsid protein of SARS-like coronavirus generates humoral and cellular immune responses

Continuous efforts have been made to develop a prophylactic vaccine against severe acute respiratory syndrome coronavirus (SARS-CoV). In this study, two recombinant baculoviruses, vAc-N and vAc-S, were constructed, which contained the mammalian-cell activate promoter element, human elongation factor...

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Detalles Bibliográficos
Autores principales: Bai, Bingke, Lu, Xinya, Meng, Jin, Hu, Qinxue, Mao, Panyong, Lu, Baojing, Chen, Ze, Yuan, Zhiming, Wang, Hanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112626/
https://www.ncbi.nlm.nih.gov/pubmed/17905435
http://dx.doi.org/10.1016/j.molimm.2007.08.010