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Use of camel single-domain antibodies for the diagnosis and treatment of zoonotic diseases

Camelids produce both conventional heterotetrameric antibodies and homodimeric heavy-chain only antibodies. The antigen-binding region of such homodimeric heavy-chain only antibodies consists of one single domain, called VHH. VHHs provide many advantages over conventional full-sized antibodies and c...

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Detalles Bibliográficos
Autores principales: Lafaye, Pierre, Li, Tengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112682/
https://www.ncbi.nlm.nih.gov/pubmed/30396425
http://dx.doi.org/10.1016/j.cimid.2018.09.009