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Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells

The endoplasmic reticulum (ER) is a highly dynamic network of membranes. Here, we combine live-cell microscopy with in situ cryo–electron tomography to directly visualize ER dynamics in several secretory cell types including pancreatic β-cells and neurons under near-native conditions. Using these im...

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Detalles Bibliográficos
Autores principales: Carter, Stephen D., Hampton, Cheri M., Langlois, Robert, Melero, Roberto, Farino, Zachary J., Calderon, Michael J., Li, Wen, Wallace, Callen T., Tran, Ngoc Han, Grassucci, Robert A., Siegmund, Stephanie E., Pemberton, Joshua, Morgenstern, Travis J., Eisenman, Leanna, Aguilar, Jenny I., Greenberg, Nili L., Levy, Elana S., Yi, Edward, Mitchell, William G., Rice, William J., Wigge, Christoph, Pilli, Jyotsna, George, Emily W., Aslanoglou, Despoina, Courel, Maïté, Freyberg, Robin J., Javitch, Jonathan A., Wills, Zachary P., Area-Gomez, Estela, Shiva, Sruti, Bartolini, Francesca, Volchuk, Allen, Murray, Sandra A., Aridor, Meir, Fish, Kenneth N., Walter, Peter, Balla, Tamas, Fass, Deborah, Wolf, Sharon G., Watkins, Simon C., Carazo, José María, Jensen, Grant J., Frank, Joachim, Freyberg, Zachary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112762/
https://www.ncbi.nlm.nih.gov/pubmed/32270040
http://dx.doi.org/10.1126/sciadv.aay9572