Inhibition of protective immunity against Staphylococcus aureus infection by MHC-restricted immunodominance is overcome by vaccination

Recurrent Staphylococcus aureus infections are common, despite robust immune responses. S. aureus infection elicited protective antibody and T cell responses in mice that expressed the Major Histocompatibility Complex (MHC) of the H-2(d) haplotype, but not H-2(b), demonstrating that host genetics dr...

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Detalles Bibliográficos
Autores principales: Si, Youhui, Zhao, Fan, Beesetty, Pavani, Weiskopf, Daniela, Li, Zhaotao, Tian, Qiaomu, Alegre, Maria-Luisa, Sette, Alessandro, Chong, Anita S., Montgomery, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112766/
https://www.ncbi.nlm.nih.gov/pubmed/32270029
http://dx.doi.org/10.1126/sciadv.aaw7713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112766/
https://www.ncbi.nlm.nih.gov/pubmed/32270029
http://dx.doi.org/10.1126/sciadv.aaw7713

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