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CpG DNA facilitate the inactivated transmissible gastroenteritis virus in enhancing the local and systemic immune response of pigs via oral administration

Transmissible gastroenteritis virus (TGEV) replicates in the small intestine and induces enteritis and watery diarrhea. Establishment of local immunity in the intestine would thus prevent TGEV transmission. CpG DNA has been reported as a promising mucosal adjuvant in some animals. The effects of ora...

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Detalles Bibliográficos
Autores principales: Lin, Jian, Tu, Chongzhi, Mou, Chunxiao, Chen, Xiaojuan, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112793/
https://www.ncbi.nlm.nih.gov/pubmed/27032496
http://dx.doi.org/10.1016/j.vetimm.2016.02.013