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CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8(+) T cells

Similar to CD4(+) T cells, precursor CD8(+) T cells are thought to depend on a co-stimulatory signal through CD28 for proliferation and differentiation into effector cells. CD46 is another co-stimulatory receptor that promotes differentiation of CD4(+) T-helper cells type 1 (Th1 cells) into a regula...

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Detalles Bibliográficos
Autores principales: Hansen, Aida S., Slater, Josefine, Biltoft, Mette, Bundgaard, Bettina B., Møller, Bjarne K., Höllsberg, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Federation of Immunological Societies. Published by Elsevier B.V. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112827/
https://www.ncbi.nlm.nih.gov/pubmed/29902483
http://dx.doi.org/10.1016/j.imlet.2018.06.003