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CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8(+) T cells
Similar to CD4(+) T cells, precursor CD8(+) T cells are thought to depend on a co-stimulatory signal through CD28 for proliferation and differentiation into effector cells. CD46 is another co-stimulatory receptor that promotes differentiation of CD4(+) T-helper cells type 1 (Th1 cells) into a regula...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Federation of Immunological Societies. Published by Elsevier B.V.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112827/ https://www.ncbi.nlm.nih.gov/pubmed/29902483 http://dx.doi.org/10.1016/j.imlet.2018.06.003 |