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A novel method for high-throughput screening to quantify antiviral activity against viruses that induce limited CPE

For antiviral screenings purposes, infection of cell cultures with the virus under study, should ideally result in the induction, within just a few days, of (nearly) complete CPE and allow the calculation of acceptable Z’ factors (>0.5). The human Corona virus NL63 (HCoV-NL63) causes only limited...

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Detalles Bibliográficos
Autores principales: Jochmans, Dirk, Leyssen, Pieter, Neyts, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112866/
https://www.ncbi.nlm.nih.gov/pubmed/22575574
http://dx.doi.org/10.1016/j.jviromet.2012.04.011