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Porcine reproductive and respiratory syndrome virus inhibition of interferon-β transcription by IRF3-independent mechanisms in MARC-145 cells in early infection

Interferon β is an important antiviral molecule whose expression is triggered through recognition of viral components by pattern recognition receptors via a cascade of signaling molecules, while viruses could target these molecules to evade from innate immunity. IFN regulatory factor 3 (IRF3) plays...

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Detalles Bibliográficos
Autores principales: Hu, Hongxia, Zhang, Xian, Zhang, Hansong, Wen, Guilan, Zhang, Qianqian, Li, Xiaoliang, Fang, Weihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112902/
https://www.ncbi.nlm.nih.gov/pubmed/24148827
http://dx.doi.org/10.1016/j.vetimm.2013.09.015