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siRNAs targeting terminal sequences of the SARS-associated coronavirus membrane gene inhibit M protein expression through degradation of M mRNA

SARS-associated coronavirus (SCoV) M protein plays a key role in viral assembly and budding. Recent studies revealed that M protein could interact with N protein in the Golgi complex. In this study, we showed that SCoV M protein co-localized in the Golgi apparatus with a Golgi vector marker. To stud...

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Detalles Bibliográficos
Autores principales: Qin, Zhao-ling, Zhao, Ping, Cao, Ming-mei, Qi, Zhong-tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112935/
https://www.ncbi.nlm.nih.gov/pubmed/17590445
http://dx.doi.org/10.1016/j.jviromet.2007.05.017