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Measles virus nucleo- and phosphoproteins form liquid-like phase-separated compartments that promote nucleocapsid assembly

Many viruses are known to form cellular compartments, also called viral factories. Paramyxoviruses, including measles virus, colocalize their proteomic and genomic material in puncta in infected cells. We demonstrate that purified nucleoproteins (N) and phosphoproteins (P) of measles virus form liqu...

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Detalles Bibliográficos
Autores principales: Guseva, Serafima, Milles, Sigrid, Jensen, Malene Ringkjøbing, Salvi, Nicola, Kleman, Jean-Philippe, Maurin, Damien, Ruigrok, Rob W. H., Blackledge, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112944/
https://www.ncbi.nlm.nih.gov/pubmed/32270045
http://dx.doi.org/10.1126/sciadv.aaz7095