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The unconventional biogenesis of Kv7.1-KCNE1 complexes

The potassium channel Kv7.1 associates with the KCNE1 regulatory subunit to trigger cardiac I(Ks) currents. Although the Kv7.1/KCNE1 complex has received much attention, the subcellular compartment hosting the assembly is the subject of ongoing debate. Evidence suggests that the complex forms either...

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Detalles Bibliográficos
Autores principales: Oliveras, Anna, Serrano-Novillo, Clara, Moreno, Cristina, de la Cruz, Alicia, Valenzuela, Carmen, Soeller, Christian, Comes, Núria, Felipe, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112945/
https://www.ncbi.nlm.nih.gov/pubmed/32270035
http://dx.doi.org/10.1126/sciadv.aay4472