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Predictive value of CD73 expression for the efficacy of immune checkpoint inhibitors in NSCLC

BACKGROUND: CD73 induces the dephosphorylation of adenosine monophosphate converting it to adenosine, enabling malignancies to escape from immune surveillance. Although CD73 overexpression has been reported to be a poor prognostic factor in several malignancies including non‐small cell lung cancer (...

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Detalles Bibliográficos
Autores principales: Ishii, Hidenobu, Azuma, Koichi, Kawahara, Akihiko, Kinoshita, Takashi, Matsuo, Norikazu, Naito, Yoshiko, Tokito, Takaaki, Yamada, Kazuhiko, Akiba, Jun, Hoshino, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113063/
https://www.ncbi.nlm.nih.gov/pubmed/32061060
http://dx.doi.org/10.1111/1759-7714.13346