Hemolysis and Fetal Fraction in Cell-Free DNA Blood Collection Tubes for Noninvasive Prenatal Testing

BACKGROUND: Lysis of maternal white blood cells in prenatal cell-free DNA (cfDNA) test samples increases the level of maternal DNA and consequently decreases fetal fraction. OBJECTIVE: The objective of this study was to determine whether hemolysis, traditionally used as a marker for cell lysis, is c...

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Detalles Bibliográficos
Autores principales: Stokowski, Renee, White, Karen, Hacker, Coleen, Doshi, Jigna, Schmid, Maximilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113221/
https://www.ncbi.nlm.nih.gov/pubmed/32056107
http://dx.doi.org/10.1007/s40291-020-00446-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113221/
https://www.ncbi.nlm.nih.gov/pubmed/32056107
http://dx.doi.org/10.1007/s40291-020-00446-x

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