CD44 Receptor Mediates Urate Crystal Phagocytosis by Macrophages and Regulates Inflammation in A Murine Peritoneal Model of Acute Gout

Gout is a chronic arthritis caused by the deposition of poorly soluble monosodium urate monohydrate (MSU) crystals in peripheral joints. Resident macrophages initiate inflammation in response to MSU mediated by NF-κB nuclear translocation and NLRP3 inflammasome activation. We investigated the role o...

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Detalles Bibliográficos
Autores principales: Bousoik, Emira, Qadri, Marwa, Elsaid, Khaled A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113258/
https://www.ncbi.nlm.nih.gov/pubmed/32238827
http://dx.doi.org/10.1038/s41598-020-62727-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113258/
https://www.ncbi.nlm.nih.gov/pubmed/32238827
http://dx.doi.org/10.1038/s41598-020-62727-z

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