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Generation of novel affibody molecules targeting the EBV LMP2A N-terminal domain with inhibiting effects on the proliferation of nasopharyngeal carcinoma cells

Nasopharyngeal carcinoma (NPC) induced by latent infection with Epstein-Barr virus (EBV) remains the most common head and neck cancer in Southeast Asia, especially in the southern part of China. It is well known that persistent expression of two EBV latent membrane proteins (LMP1/LMP2A) plays a key...

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Detalles Bibliográficos
Autores principales: Zhu, Jinshun, Kamara, Saidu, Cen, Danwei, Tang, Wanlin, Gu, Meiping, Ci, Xingyuan, Chen, Jun, Wang, Lude, Zhu, Shanli, Jiang, Pengfei, Chen, Shao, Xue, Xiangyang, Zhang, Lifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113277/
https://www.ncbi.nlm.nih.gov/pubmed/32238802
http://dx.doi.org/10.1038/s41419-020-2410-7