MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3β/β-catenin signaling

Structural variations (SVs) influence the development and progression of multiple types of cancer. The genes affected by SVs in hepatocellular carcinoma (HCC) and their contribution to tumor growth and metastasis remain unknown. In this study, through whole-genome sequencing (WGS), we identified MAC...

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Detalles Bibliográficos
Autores principales: Zhou, Zheng-Jun, Luo, Chu-Bin, Xin, Hao-Yang, Hu, Zhi-Qiang, Zhu, Gui-Qi, Li, Jia, Zhou, Shao-Lai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113304/
https://www.ncbi.nlm.nih.gov/pubmed/32257385
http://dx.doi.org/10.1038/s41525-020-0122-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113304/
https://www.ncbi.nlm.nih.gov/pubmed/32257385
http://dx.doi.org/10.1038/s41525-020-0122-7

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