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A GLP-1 Analog Liraglutide Reduces Intimal Hyperplasia After Coronary Stent Implantation via Regulation of Glycemic Variability and NLRP3 Inflammasome/IL-10 Signaling in Diabetic Swine

OBJECTIVE: This study aimed to explore whether treatment with the glucagon-like peptide-1 (GLP-1) analog liraglutide reduces intimal hyperplasia after coronary stent implantation via regulation of glycemic variability, the NLRP3 inflammasome, and IL-10 in diabetic swine. METHODS: Fifteen pigs were d...

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Detalles Bibliográficos
Autores principales: Xia, Jinggang, Li, Qinxue, Liu, Yayun, Ren, Quanxin, Gao, Jinhuan, Tian, Yi, Li, Jubo, Zhang, Baojie, Sun, Haichen, Liu, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113385/
https://www.ncbi.nlm.nih.gov/pubmed/32273846
http://dx.doi.org/10.3389/fphar.2020.00372