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Effects of Genetic and Pharmacologic Inhibition of COX-2 on Colitis-associated Carcinogenesis in Mice

COX-2 has been inappropriately overexpressed in various human malignancies, and is considered as one of the representative targets for the chemoprevention of inflammation-associated cancer. In order to assess the role of COX-2 in colitis-induced carcinogenesis, the selective COX-2 inhibitor celecoxi...

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Detalles Bibliográficos
Autores principales: Lee, Jeong-Sang, Kim, Hyun Soo, Hahm, Ki Baik, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113413/
https://www.ncbi.nlm.nih.gov/pubmed/32266177
http://dx.doi.org/10.15430/JCP.2020.25.1.27