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BRS3 in both MC4R- and SIM1-expressing neurons regulates energy homeostasis in mice

OBJECTIVE: Bombesin-like receptor 3 (BRS3) is an orphan receptor and Brs3 knockout mice develop obesity with increased food intake and reduced resting metabolic rate and body temperature. The neuronal populations contributing to these effects were examined. METHODS: We studied energy metabolism in m...

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Detalles Bibliográficos
Autores principales: Xiao, Cuiying, Liu, Naili, Province, Haley, Piñol, Ramón A., Gavrilova, Oksana, Reitman, Marc L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113433/
https://www.ncbi.nlm.nih.gov/pubmed/32229422
http://dx.doi.org/10.1016/j.molmet.2020.02.012