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Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus

SynNotch receptor technology is a versatile tool that uses the regulatory notch core portion with an extracellular scFv and an intracellular transcription factor that enables to program customized input and output functions in mammalian cells. In this study, we designed a novel synNotch receptor com...

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Detalles Bibliográficos
Autores principales: Matsunaga, Satoko, Jeremiah, Sundararaj S., Miyakawa, Kei, Kurotaki, Daisuke, Shizukuishi, Sayaka, Watashi, Koichi, Nishitsuji, Hironori, Kimura, Hirokazu, Tamura, Tomohiko, Yamamoto, Naoki, Shimotohno, Kunitada, Wakita, Takaji, Ryo, Akihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113479/
https://www.ncbi.nlm.nih.gov/pubmed/32105634
http://dx.doi.org/10.1016/j.isci.2020.100867