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Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus
SynNotch receptor technology is a versatile tool that uses the regulatory notch core portion with an extracellular scFv and an intracellular transcription factor that enables to program customized input and output functions in mammalian cells. In this study, we designed a novel synNotch receptor com...
Autores principales: | Matsunaga, Satoko, Jeremiah, Sundararaj S., Miyakawa, Kei, Kurotaki, Daisuke, Shizukuishi, Sayaka, Watashi, Koichi, Nishitsuji, Hironori, Kimura, Hirokazu, Tamura, Tomohiko, Yamamoto, Naoki, Shimotohno, Kunitada, Wakita, Takaji, Ryo, Akihide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113479/ https://www.ncbi.nlm.nih.gov/pubmed/32105634 http://dx.doi.org/10.1016/j.isci.2020.100867 |
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