In vivo multiplex gene targeting with Streptococcus pyogens and Campylobacter jejuni Cas9 for pancreatic cancer modeling in wild-type animal

Pancreatic ductal adenocarcinoma is a lethal cancer type that is associated with multiple gene mutations in somatic cells. Genetically engineered mouse is hardly applicable for developing a pancreatic cancer model, and the xenograft model poses a limitation in the reflection of early stage pancreati...

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Detalles Bibliográficos
Autores principales: Chang, Yoo Jin, Bae, Jihyeon, Zhao, Yang, Lee, Geonseong, Han, Jeongpil, Lee, Yoon Hoo, Koo, Ok Jae, Seo, Sunmin, Choi, Yang-Kyu, Yeom, Su Cheong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Veterinary Science 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113579/
https://www.ncbi.nlm.nih.gov/pubmed/32233134
http://dx.doi.org/10.4142/jvs.2020.21.e26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113579/
https://www.ncbi.nlm.nih.gov/pubmed/32233134
http://dx.doi.org/10.4142/jvs.2020.21.e26

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