An image-based Pathogen Box screen identifies new compounds with anti-Giardia activity and highlights the importance of assay choice in phenotypic drug discovery

Giardia duodenalis, the most prevalent human intestinal parasite causes the disease, giardiasis. On an annual basis G. duodenalis infects ~1 billion people, of which ~280 million develop symptomatic disease. Giardiasis can be severe and chronic, causing malnutrition, stunted growth and poor cognitiv...

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Detalles Bibliográficos
Autores principales: Tiash, Snigdha, Saunders, Jake, Hart, Christopher J.S., Ryan, John H., Riches, Andrew G., Skinner-Adams, Tina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113605/
https://www.ncbi.nlm.nih.gov/pubmed/32234669
http://dx.doi.org/10.1016/j.ijpddr.2020.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113605/
https://www.ncbi.nlm.nih.gov/pubmed/32234669
http://dx.doi.org/10.1016/j.ijpddr.2020.03.002

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