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Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery

Adeno-associated virus (AAV) is being used successfully in gene therapy. Different serotypes of AAV target specific organs and tissues with high efficiency. There exists an increasing demand to manufacture various AAV serotypes in large quantities for pre-clinical and clinical trials. A generic and...

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Detalles Bibliográficos
Autores principales: Chahal, Parminder Singh, Schulze, Erica, Tran, Rosa, Montes, Johnny, Kamen, Amine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113661/
https://www.ncbi.nlm.nih.gov/pubmed/24239634
http://dx.doi.org/10.1016/j.jviromet.2013.10.038