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Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein

The multi-domain non-structural protein 3 (Nsp3) is the largest protein encoded by the coronavirus (CoV) genome, with an average molecular mass of about 200 kD. Nsp3 is an essential component of the replication/transcription complex. It comprises various domains, the organization of which differs be...

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Detalles Bibliográficos
Autores principales: Lei, Jian, Kusov, Yuri, Hilgenfeld, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113668/
https://www.ncbi.nlm.nih.gov/pubmed/29128390
http://dx.doi.org/10.1016/j.antiviral.2017.11.001