Identification of a peptide derived from the heptad repeat 2 region of the porcine epidemic diarrhea virus (PEDV) spike glycoprotein that is capable of suppressing PEDV entry and inducing neutralizing antibodies

Heptad repeat (HR) regions are highly conserved motifs located in the glycoproteins of enveloped viruses that form a six-helix bundle structure and is important in the process of virus fusion. Peptides derived from the HR regions of some viruses have also been shown to inhibit viral entry. Porcine e...

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Detalles Bibliográficos
Autores principales: Zhao, Pengwei, Wang, Bin, Ji, Chun-Miao, Cong, Xiaoyan, Wang, Ming, Huang, Yao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113693/
https://www.ncbi.nlm.nih.gov/pubmed/29203391
http://dx.doi.org/10.1016/j.antiviral.2017.11.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113693/
https://www.ncbi.nlm.nih.gov/pubmed/29203391
http://dx.doi.org/10.1016/j.antiviral.2017.11.021

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